915024-77-0

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 914936-51-9 (2S)-1-(t-butyldiphenylsiloxy)-2-(p-methoxybenzyloxy)-28-(tetrahydro-2H-pyran-2-yloxy)octacosane-24-ol 
• 103708-37-8 (2S,4S)-4-hydroxymethyl-2-(p-methoxymethyl)-1,3-dioxane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 221677-48-1 (3S)-4-[1-(tert-butyl)-1,1-diphenylsilyl]oxy-3-[(4-methoxybenzyl)oxy]butan-1-ol 
• 231299-11-9 (2S,4S)-tert-butyl-[2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethoxy]-diphenyl-silane 
• 914936-41-7 (2S)-14-(t-butyldimethylsiloxy)-1-(t-butyldiphenylsiloxy)-2-(p-methoxybenzyloxy)tetradecane 
• 914936-85-9 (13S)-14-(t-butyldiphenylsiloxy)-13-(p-methoxybenzyloxy)tetradecanol 
• 914936-43-9 (2S)-1-(t-butyldiphenylsiloxy)-14-iodo-2-(p-methoxybenzyloxy)tetradecane 
• 914936-39-3 (2S)-1-(t-butyldiphenylsiloxy)-4-iodo-2-(p-methoxybenzyloxy)butane 
• 914936-49-5 (23S)-24-(t-butyldiphenylsiloxy)-23-(p-methoxybenzyloxy)tetradecanal 
• 914936-46-2 (2S)-24-(t-butyldimethylsiloxy)-1-(t-butyldiphenylsiloxy)-2-(p-methoxybenzyloxy)tetracosane 
• 914936-88-2 (23S)-24-(t-butyldiphenylsiloxy)-23-(p-methoxybenzyloxy)tetradecanol 

Downstream Products

• 915024-78-1 (2S)-2-(p-methoxybenzyloxy)-24,28-di(tetrahydro-2H-pyran-2-yloxy)octacosanol 
• 914936-57-5 (2S)-24-hydroxy-2-(p-methoxybenzyloxy)octacosanolide 
• 914936-92-8 (2S)-2-(p-methoxybenzyloxy)-24-oxooctacosanolide 
• 914936-55-3 (2S)-24,28-dihydroxy-2-(p-methoxybenzyloxy)octacosanoic acid 
• 914936-94-0 (2R)-2-(3,5-dinitrobenzoyloxy)-24-oxooctacosanolide 
• 915024-80-5 (2S)-2-(p-methoxybenzyloxy)-24,28-di(tetrahydro-2H-pyran-2-yloxy)octacosanoic acid 

Relevant academic research and scientific papers

METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER AND NOVEL INTERMEDIATE COMPOUND

Disclosed is a method for producing an optically active 2-hydroxy ester, comprising selectively esterifying one enantiomer of a racemic 2-hydroxy ester in a solvent containing a catalyst such as tetramisole or benzotetramisole, and a carboxylic acid anhydride, or a carboxylic acid anhydride and a carboxylic acid. In particular, in the case where the solvent contains a carboxylic acid anhydride, but does not contain a carboxylic acid, as the carboxylic acid anhydride, a carboxylic acid anhydride containing a tertiary or quaternary carbon atom in the a-position is used. On the other hand, in the case where the solvent contains a carboxylic acid anhydride and a carboxylic acid, as the carboxylic acid, a carboxylic acid containing a tertiary or quaternary carbon atom in the a-position is used.

The first total synthesis of (-) and (+)-2-hydroxy-24-oxooctacosanolide using an effective lactonization

(Chemical Equation Presented) An effective method for the total synthesis of 2-hydroxy-24-oxooctacosanolide, a defensive salivary secretion of the African termite Pseudacanthotermes spiniger, has been developed. The key lactonization to form a 29-membered ring lactone core is performed using 2-methyl-6- nitrobenzoic anhydride with a catalytic amount of 4-(dimethylamino)pyridine N-oxide.