91509-69-2Relevant academic research and scientific papers
3-aryl-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butyramide and derivatives as antifungal agents
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, (2008/06/13)
Compounds of the formula STR1 or a pharmaceutically or agriculturally acceptable acid addition salt thereof, wherein R is 5-chloro-2-pyridyl, or phenyl optionally substituted by one to three substituents, each independently selected from F, Cl, Br, I, CF3, C1 -C4 alkyl and C1 -C4 alkoxy; R1 is CN, CSNH2 or CONR2 R3 where either (a) R2 is H or certain alkyl groups and R3 is H or certain alkyl, substituted alkyl, aralkyl, phenyl or cycloalkyl groups, or (b) R2 and R3 taken together with the nitrogen atom to which they are attached form a nitrogen heterocyclic group, optionally containing an oxygen atom or NR4 group, as a ring member and R4 is H, C1 -C4 alkyl; C2 -C4 alkanoyl or (C1 -C4 alkoxy)carbonyl; R5 and R6 are each H or CH3 ; methods for their use in combatting fungal infections in plants, seeds and animals, including humans, pharmaceutical and agricultural compositions containing them and intermediates therefor.
N-Acyl 3-aryl-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-butyramide antifungal agents
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, (2008/06/13)
Compounds of the formula STR1 a pharmaceutically or agriculturally acceptable salt thereof, wherein R is 5-chloro-2-pyridyl or phenyl optionally substituted by one to three substituents, each independently selected from F, Cl, Br, I, CF3, C1 -C4 alkyl and C1 -C4 alkoxy; R1 is CONR2 R3 where either (a) R2 is H or C1 -C4 alkyl and R3 is C2 -C4 alkanoyl or optionally substituted benzoyl; or (b) R2 and R3 are each (C1 -C4 alkoxy)carbonyl; and R4 and R5 are each H or CH3 ; methods for their use in combating fungal infections in plants, seeds and animals, including humans, and pharmaceutical and agricultural compositions containing them.
Triazole antifungal agents
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, (2008/06/13)
Compounds of the general formula: STR1 wherein Ar is dichlorophenyl and Het is 1-methyltetrazol-5-yl, 1,2,4-triazol-3-yl, 1-methyl-1,2,4-triazol-3-yl, 2-methyl-1,2,4-triazol-3-yl, 4-methyl-1,2,4-triazol-3-yl, imidazol-2-yl or 1-methylimidazol-2-yl and the
