915094-69-8

Upstream product

• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 915094-66-5 2-((S)-1-Benzyloxycarbonylamino-2-hydroxy-ethyl)-oxazole-4-carboxylic acid methyl ester 
• 203456-94-4 2-((S)-1-amino-2-hydroxyethyl)oxazole-4-carboxylic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 104499-27-6 (S)-2-benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid 
• 915094-65-4 2-[(S)-1-benzyloxycarbonylamino-2-(tert-butyldimethylsilanyloxy)ethyl]oxazole-4-carboxylic acid 
• 915094-64-3 2-[(S)-1-benzyloxycarbonylamino-2-(tert-butyldimethylsilanyloxy)ethyl]oxazole-4-carboxylic acid methyl ester 
• 915094-63-2 (S)-2-[(S)-2-benzyloxycarbonylamino-3-(tert-butyldimethylsilanyloxy)propionylamino]-3-hydroxypropionic acid methyl ester 
• 915094-67-6 2-[(S)-1-({2-[(S)-1-benzyloxycarbonylamino-2-(tert-butyldimethylsilanyloxy)ethyl]oxazole-4-carbonyl}amino)-2-hydroxyethyl]oxazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Design and synthesis of telomestatin derivatives and their inhibitory activity of telomerase

Telomestatin derivatives of 2a-2c, which have macrocyclic bisamide structure, were designed and synthesized. One of these compounds (2a) showed inhibitory activity of telomerase with an 1C50 of 2μM.