915097-25-5

Upstream product

• 108-91-8 cyclohexylamine 
• 3056-18-6 (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(2,6-dichloro-9H-purin-9-yl)tetrahydro-3-furanyl acetate 
• 920974-75-0 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-chloro-6-(cyclohexylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 920974-77-2 (2R,3R,4S,5R)-2-(6-Cyclohexylamino-2-hydrazino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 
• 80370-42-9 ethyl 2-formyl-3-oxopropanoate 

Relevant academic research and scientific papers

N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists

A series of new selective, high affinity A1-AdoR agonists is reported. Compound 23 that incorporated a carboxylic acid functionality in the 4-position of the pyrazole ring displayed KiL value of 1 nM for the A1-AdoR and >5