915124-56-0Relevant academic research and scientific papers
Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors
Angibaud, Patrick,Emelen, Kristof Van,Decrane, Laurence,Brandt, Sven van,Holte, Peter ten,Pilatte, Isabelle,Roux, Bruno,Poncelet, Virginie,Speybrouck, David,Queguiner, Laurence,Gaurrand, Sandrine,Marien, Ann,Floren, Wim,Janssen, Lut,Verdonck, Marc,Dun, Jacky van,Gompel, Jacky van,Gilissen, Ron,Mackie, Claire,Jardin, Marc Du,Peeters, Jozef,Noppe, Marc,Hijfte, Luc Van,Freyne, Eddy,Page, Martin,Janicot, Michel,Arts, Janine
scheme or table, p. 294 - 298 (2010/04/06)
Pursuing our efforts in designing 5-pyrimidylhydroxamic acid anti-cancer agents, we have identified a new series of potent histone deacetylase (HDAC) inhibitors. These compounds exhibit enzymatic HDAC inhibiting properties with IC50 values in t
