915154-71-1

Basic information

• Product Name: 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranuronamide
• Synonyms: 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranuronamide
• CAS NO: 915154-71-1
• Molecular Weight: 323.346
• Mol File: 915154-71-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranuronamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranuronamide(915154-71-1)
• EPA Substance Registry System: 3-O-benzyl-1,2-O-isopropylidene-β-L-idopyranuronamide(915154-71-1)

Safety Data

• Hazardous Substances Data: 915154-71-1(Hazardous Substances Data)

Upstream product

• 915154-70-0 C₁₆H₁₉NO₅ 

Downstream Products

• 87326-76-9 methyl 3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranosiduronate 
• 444118-44-9 1,2-O-isopropylidene-3-O-benzyl-4-O-trichloroacetyl-6-methyl-α-L-idonic acid 
• 1190921-28-8 C₃₆H₄₀N₄O₁₀ 

Relevant articles and documents

Scalable synthesis of L-lduronic acid derivatives via stereocontrolled cyanohydrin reaction for synthesis of heparin-related disaccharides

L-ldo cyanohydrln 3 was prepared from dlacetone-D-glucose In four steps and 76% overall yield and 90% de via cyanohydrin reaction of aldehyde 2. This process can be scaled to provide >1 mol of pure L-Ido cyanohydrin 3. Cyanohydrin 3 was elaborated to 1,2-Isopropylldineprotected L-ldo nitrile (8), lduronic amide 9, and known carboxy ester 10. Coupling of 8 and 9 with glucosamine donors leads to new types (6-cyano and 6-carboxamlde) of heparin-related disaccharides.