915221-66-8

Upstream product

• 538370-37-5 Trifluoro-methanesulfonic acid (2R,4aR,6R,7S,8S,8aR)-7-benzyloxy-8-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl ester 
• 177943-74-7 methyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-1-thio-α-D-mannopyranoside 
• 538370-38-6 (2R,4aR,6S,7S,8S,8aR)-6-((2R,3S,4R,5R,6R)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-pent-4-enyloxy-tetrahydro-pyran-3-yloxy)-7-benzyloxy-8-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine 

Downstream Products

• 538370-42-2 C₇₁H₈₆N₆O₁₄Si 
• 538370-39-7 [(2R,4aR,6S,7S,8S,8aR)-6-((2R,3S,4R,5R,6R)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-pent-4-enyloxy-tetrahydro-pyran-3-yloxy)-7-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

A short synthesis of the trisaccharide building block of the N-linked glycans

An efficient preparation of the core trisaccharide of N-linked glycoproteins containing β-azido functionality at the reducing terminus is described. In the synthesis, triflate-mediated direct β-mannosylation was employed for the formation of the β-D-Man-(1→4)-GlcNAc linkage; the anomeric azide installation was achieved through oxazoline ring opening.