177943-74-7

Basic information

• Product Name: a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thio-
• Synonyms: a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thio-;Phenyl 3-O-[(4-methoxyphenyl)methyl]-2-O-(phenylmethyl)-4,6-O-[(R)-phenylmethylene]-1-thio-alpha-D-mannopyranoside
• CAS NO: 177943-74-7
• Molecular Formula: C₃₄H₃₄O₆S
• Molecular Weight: 570.69516
• Mol File: 177943-74-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thio-(CAS DataBase Reference)
• NIST Chemistry Reference: a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thio-(177943-74-7)
• EPA Substance Registry System: a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thio-(177943-74-7)

Safety Data

• Hazardous Substances Data: 177943-74-7(Hazardous Substances Data)

Usage

Uses

1. Used in Pharmaceutical Industry:
a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thiois used as a reactant in the synthetic approach to the glycan chain of high mannose type N-glycoprotein. This application is significant because N-glycoproteins play a crucial role in various biological processes, including cell adhesion, immune response, and protein folding. The compound's ability to contribute to the synthesis of these proteins makes it a valuable tool in the development of new drugs and therapies.
2. Used in Chemical Research:
Due to its unique structure and reactivity, a-D-Mannopyranoside, phenyl 3-O-[(4-Methoxyphenyl)Methyl]-2-O-(phenylMethyl)-4,6-O-[(R)-phenylMethylene]-1-thiocan be employed in chemical research to explore new reactions and develop novel synthetic pathways. Its potential as a building block for more complex molecules makes it an interesting candidate for further investigation in the field of organic chemistry.

Upstream product

• 100-39-0 benzyl bromide 
• 168138-26-9 phenyl 4,6-O-benzylidene-3-O-(4-methoxybenzyl)-1-thio-α-D-mannopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 2936-70-1 (2R,3S,4S,5S,6R)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol 
• 159407-19-9 phenyl 4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 83-87-4 D-Mannose pentaacetate 
• 108-98-5 thiophenol 

Downstream Products

• 158716-08-6 phenyl 4,6-O-benzylidene-2-O-benzyl-1-deoxy-1-thio-α-D-mannopyranoside 
• 538370-37-5 Trifluoro-methanesulfonic acid (2R,4aR,6R,7S,8S,8aR)-7-benzyloxy-8-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl ester 
• 915221-66-8 (2R,4aR,6S,7S,8S,8aS)-6-((2R,3S,4R,5R,6R)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-pent-4-enyloxy-tetrahydro-pyran-3-yloxy)-7-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 
• 538370-39-7 [(2R,4aR,6S,7S,8S,8aR)-6-((2R,3S,4R,5R,6R)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-pent-4-enyloxy-tetrahydro-pyran-3-yloxy)-7-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-tert-butyl-dimethyl-silane 
• 538370-38-6 (2R,4aR,6S,7S,8S,8aR)-6-((2R,3S,4R,5R,6R)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-pent-4-enyloxy-tetrahydro-pyran-3-yloxy)-7-benzyloxy-8-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 538370-42-2 C₇₁H₈₆N₆O₁₄Si 
• 158716-10-0 phenyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-1-deoxy-1-thio-α-D-mannopyranoside 
• 216758-86-0 methyl (2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranosyl)-(1-2)-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside 
• 216758-83-7 methyl (3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranosyl)-(1-2)-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside 
• 216758-89-3 methyl (2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1-3)-(2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranosyl)-(1-2)-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside 
• 1294354-20-3 2-O-benzyl-4,6-O-benzylidene-3-O-((4-methoxyphenyl)methyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl azide 
• 1342309-90-3 benzyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 1342309-91-4 benzyl 2-O-benzyl-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 1342309-92-5 benzyl 2-O-benzyl-6-O-tert-butyldimethylsilyl-3-O-p-methoxybenzyl-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 

Relevant articles and documents

A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate against Klebsiella pneumoniae Serotype K2

Klebsiella pneumoniae causes pneumonia and liver abscesses in humans worldwide and contains virulence factor capsular polysaccharides and lipopolysaccharides linked to the cell wall. Although capsular polysaccharides are good antigens for vaccine producti

ANTIBODY CONJUGATES AND METHODS OF MAKING THE ANTIBODY CONJUGATES

Described herein are antibody conjugates and methods of making antibody conjugates.

Direct chemical synthesis of the β-mannans: Linear and block syntheses of the alternating β-(1→3)-β-(1→4)-mannan common to Rhodotorula glutinis, Rhodotorula mucilaginosa, and Leptospira biflexa

Two stereocontrolled syntheses of a methyl glycoside of an alternating β-(1→4)-β-(1→3)-mannohexaose, representative of the mannan from Rhodotorula glutinis, Rhodotorula mucilaginosa, and Leptospira biflexa, are described. Both syntheses employ a combinati

A synthetic approach to the glycan chain of high mannose type N-glycoprotein

The syntheses of α-D-glucopyranose-(1→3)-D-mannopyranose, methyl α-D-glucopyranose-(1→3)-α-D-mannopyranoside and methyl α-D-glucopyranose-(1→3)-α-D-mannopyranose-(1→2)-α-D- mannopyranoside are reported. High stereoselectivity was observed during the coupl