915282-47-2

Upstream product

• 135321-95-8 2-hydroxy-5-<(tert-butoxycarbonyl)amino>benzoic acid 
• 115-11-7 isobutene 
• 89-57-6 5-Aminosalicylic Acid 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 947152-95-6 C₂₃H₂₈N₂O₅S 
• 915282-45-0 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 5-amino-2-hydroxybenzoate 

Relevant academic research and scientific papers

NO- AND H2S- RELEASING COMPOUNDS

This disclosure relates to novel compounds containing an H2S releasing moiety and a nitric oxide (NO) releasing moiety covalently linked with a core (e.g., a salicylic acid moiety) and the use of such compounds in treating inflammatory diseases, including

NO- AND H2S- RELEASING COMPOUNDS

This disclosure relates to compounds containing both an NO-releasing moiety and an H2S-releasing moiety and the use of such compounds in treating inflammatory diseases, including cancers.

Derivaitves of 4-Or 5-Aminosalicylic Acid

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as infl

Derivatives of 4- or 5-aminosalicylic acid

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.