915315-59-2Relevant academic research and scientific papers
Nonenzymic polycyclisation of analogues of oxidosqualene with a preformed C-ring
Winne, Johan M.,De Clercq, Pierre J.,Milanesio, Marco,Pattison, Philip,Viterbo, Davide
scheme or table, p. 1918 - 1925 (2009/01/31)
Some nonenzymic epoxide-initiated polyolefin cyclisations are reported. The presented molecules are partially constrained analogues of (3S)-oxidosqualene, the natural substrate to many important cyclase enzymes. These model compounds feature a preformed C
Application of the B-alkyl Suzuki-Miyaura cross-coupling reaction to the stereoselective synthesis of analogues of (3S)-oxidosqualene
Winne, Johan M.,Guang, Bing,D'Herde, Jo,De Clercq, Pierre J.
, p. 4815 - 4818 (2007/10/03)
(Chemical Equation Presented) A general method is described for the direct and stereoselective synthesis of epoxypolyenes via Suzuki-Miyaura cross-coupling reaction of 1-iodoalkenes with B-alkylboron compounds. It allows for the straightforward and conver
