91553-38-7Relevant academic research and scientific papers
A Selective and General Cobalt-Catalyzed Hydroaminomethylation of Olefins to Amines
Beller, Matthias,Delolo, Fábio G.,Jackstell, Ralf,Spannenberg, Anke,Yang, Ji
supporting information, (2021/12/06)
A new cobalt catalyst is presented for the domino hydroformylation-reductive amination reaction of olefins. The optimal Co-tert-BuPy-Xantphos catalyst shows good to excellent linear-to-branched (n/iso) regioselectivity for the reactions of aliphatic alken
Synthesis of 3-[4-(dimethylamino)phenyl]alkyl-2-oxindole derivatives and their effects on neuronal cell death
Furuta, Kyoji,Kawai, Yu,Mizuno, Yosuke,Hattori, Yurika,Koyama, Hiroko,Hirata, Yoko
, p. 4457 - 4461 (2017/09/12)
Novel 3-[4-(dimethylamino)phenyl]alkyl-2-oxindole analogs were synthesized by either of the following two pathways: (1) a sequence of Knoevenagel condensation of oxindole with (4-dimethylamino)cinnamaldehyde–hydrogenation, or (2) alkylation of oxindole dianion with [(4-dimethylamino)phenyl]alkyl halides. Subsequent alkylation at C-3 and/or N-1 of the oxindole skeleton by anion-based methods provided additional substituted derivatives for structure-activity relationship studies. Their effects on neuronal cell death induced by oxidative stress were evaluated by lactate dehydrogenase assay. Compounds with the alkyl chain length of 2–4 significantly suppressed the neuronal cell death. No significant change occurred in the activity by substitution with less-polar groups. The stereochemistry at C-3 of the oxindole core was also irrelevant for the neuroprotective effects of these compounds.
Synthesis and characterization of a series of azobenzene-containing side-chain liquid crystalline polymers
Freiberg, Stephan,Lagugne-Labarthet, Francois,Rochon, Paul,Natansohn, Almeria
, p. 2680 - 2688 (2007/10/03)
A series of poly{4′-{(X-methacryloyloxyalkylene)methylamino}-4-nitroazobenzene} (pXMAN, where X is the number of methylene units and varies from 2 to 12) polymers with liquid crystalline (LC) properties was synthesized. When annealed above their Tg values, the whole series of polymers exhibits a stable smectic A mesophase while only the material with the shorter spacer, p2MAN, presents a smectic phase followed by a nematic phase. The spacing of the smectic layers was determined by X-ray diffraction, revealing intermolecular reorganization by interdigitation of the side-chain mesogens since the smectic layer spacing was larger than a fully extended side chain but less than two extended chains. This behavior is confirmed by temperature dependent aggregation as observed by UV-visible spectroscopy during the transition from an amorphous state to a liquid crystalline phase. The stability of the mesophase is enhanced by intermolecular interactions as argued by enthalpic and thermochromic considerations. Systematic photoinduced birefringence measurements on the various states reveal that the maximum and remnant levels of birefringence decrease with increasing the spacer length and with decreasing the glass transition temperature of the considered liquid crystalline polymer.
