91557-46-9

Basic information

• Product Name: N-(2-morpholin-4-yl-2-oxoethyl)aniline
• CAS NO: 91557-46-9
• Molecular Formula: C₁₂H₁₆N₂O₂
• Molecular Weight: 220.2676
• Mol File: 91557-46-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 443.2°C at 760 mmHg
• Flash Point: 221.8°C
• Density: 1.199g/cm³
• Vapor Pressure: 4.73E-08mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: N-(2-morpholin-4-yl-2-oxoethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-morpholin-4-yl-2-oxoethyl)aniline(91557-46-9)
• EPA Substance Registry System: N-(2-morpholin-4-yl-2-oxoethyl)aniline(91557-46-9)

Safety Data

• Hazardous Substances Data: 91557-46-9(Hazardous Substances Data)

Upstream product

• 1440-61-5 N-chloroacetylmorpholine 
• 62-53-3 aniline 
• 1421132-82-2 C₆H₁₀NO₆S^(1-)*Na⁽¹⁺⁾ 
• 16423-59-9 2-(morpholin-4-yl)-2-oxoacetaldehyde 
• 110-91-8 morpholine 
• 103-01-5 N-Phenylglycine 

Relevant articles and documents

Unnatural α-Amino Acid Synthesized through α-Alkylation of Glycine Derivatives by Diacyl Peroxides

We have developed a protocol for catalyst- and additive-free α-alkylation reactions of glycine derivatives with diacyl peroxides, which proceed by a pathway involving addition of alkyl radicals to imine intermediates. The diacyl peroxide substrate acts as both alkylation agent and oxidizing agent, which means it is atom-economical. It was applied to various glycine derivatives, dipeptides, and a 3,4-dihydroquinoxalin-2(1H)-one derivative and could be carried out on a gram scale, indicating its utility for late-stage functionalization.