91568-99-9

Upstream product

• 10531-41-6 2-Bromoacetylthiophene 
• 62-53-3 aniline 
• 88-15-3 2-Acetylthiophene 

Downstream Products

• 1609985-47-8 (Z)-(1,2-diphenyl-5-(thiophen-2-ylmethylene)-2,5-dihydro-1H-pyrazole-3,4-diyl)bis(thiophen-2-ylmethanone) 
• 177703-85-4 2-(phenylamino)-1,4-di(thiophen-2-yl)but-2-ene-1,4-dione 

Relevant academic research and scientific papers

Hypervalent iodine mediated syntheses of heterocycles: One-pot facile syntheses of 1,4-diaryl-2-mercaptoimidazoles, 2-(α-anilinoacetyl)thiophenes and 1-aryl-2-mercapto-4-(2-thienyl)imidazoles from aryl/2-thienyl methyl ketones

Successive treatment of acetophenones (1a-e) or 2-acetylthiophene (4) with benzene, appropriate aniline and KSCN/AcOH leads to the formation of 1,4-diaryl-2-mercaptoimidazoles (3aa-3ea) or 1-aryl-2-mercapto-4-(2-thienyl)imidazoles (6a-f) respectively.This procedure also provides 2(α-anilinoacetyl)thiophenes (5a-f) in one pot from 4.