915694-39-2

Upstream product

• 303963-92-0 (3aR,6aR)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-one 
• 915694-38-1 (3aR,3bR,4aS,5S,5aS)-3b-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethylhexahydrocyclopropa[3,4]cyclopenta[1,2-d][1,3]dioxol-5-ol 
• 75-24-1 trimethylaluminum 

Downstream Products

• 1355670-44-8 (1R,2R,3R,4S,5S)-2-tert-butoxy-4-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxymethyl)-bicyclo[3.1.0]hexan-3-ol 
• 1355670-94-8 (1R,2R,3S,4R,5S)-2-tert-butoxy-1-(tert-butyl-diphenylsilanyloxymethyl)-4-(6-chloro-purin-9-yl)-3-fluoromethyl-bicyclo[3.1.0]hexan-3-ol 
• 1355670-90-4 (1R,2R,3S,4R,5S)-3-azidomethyl-2-tert-butoxy-1-(tertbutyl-diphenyl-silanyloxymethyl)-4-(6-chloro-purin-9-yl)-bicyclo[3.1.0]hexan-3-ol 
• 1355670-89-1 (1S,4aR,5R,5aR,6S)-(4a-fluoromethyl-5-tert-butoxy-3,3-dioxo-tetrahydro-2,4-dioxa-3λ6-thia-cyclopropa[a]pentalen-5a-ylmethoxy)-tert-butyl-diphenyl-silane 
• 1355671-10-1 C₂₈H₃₇FO₅SSi 
• 1355670-88-0 (1S,4aR,5R,5aR,6S)-(4a-azidomethyl-5-tert-butoxy-3,3-dioxo-tetrahydro-2,4-dioxa-3λ6-thia-cyclopropa[a]pentalen-5a-ylmethoxy)-tert-butyl-diphenyl-silane 
• 1355671-09-8 C₂₈H₃₇N₃O₅SSi 
• 1355670-87-9 (1S,2S,3S,4R,5R)-4-tert-butoxy-5-(tert-butyl-diphenylsilanyloxymethyl)-3-fluoromethyl-bicyclo[3.1.0]hexane-2,3-diol 
• 1355670-86-8 (1S,2S,3S,4R,5R)-3-azidomethyl-4-tert-butoxy-5-(tertbutyl-diphenyl-silanyloxymethyl)-bicyclo[3.1.0]hexane-2,3-diol 
• 1355670-57-3 acetic acid (1R,2R,3R,4R,5S)-2-tert-butoxy-1-(tert-butyldiphenyl-silanyloxymethyl)-4-(6-chloro-purin-9-yl)-3-hydroxy-bicyclo[3.1.0]hex-3-ylmethyl ester 
• 1355670-55-1 C₃₀H₄₀O₇SSi 
• 1355670-54-0 (1S,4aR,5R,5aR,6R)-acetic acid 5-tert-butoxy-5a-(tert-butyldiphenyl-silanyloxymethyl)-3,3-dioxo-tetrahydro-2,4-dioxa-3λ6-thia-cyclopropa[a]pentalen-4a-ylmethyl ester 
• 1355670-53-9 (1R,2R,3S,4S,5S)-acetic acid 2-tert-butoxy-1-(tert-butyldiphenyl-silanyloxymethyl)-3,4-dihydroxy bicyclo[3.1.0]hex-3-ylmethyl ester 
• 1355670-50-6 (1R,2R,3R,4S,5S)-acetic acid 2-tert-butoxy-4-(tert-butyldimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-bicyclo[3.1.0]hex-3-ylmethyl ester 

Relevant academic research and scientific papers

Asymmetric synthesis of cyclopropyl-fused 2′-C-methylcarbanucleosides as potential anti-HCV agents

Novel 2′-C-methyl-cyclopropyl-fused carbocyclic nucleosides as potential anti-HCV agents were stereoselectively synthesized, utilizing regioselective cleavage of the isopropylidene group and cyclic sulfate chemistry as key steps. Copyright Taylor & Franci

Stereoselective synthesis and anti-HCV activity of conformationally restricted 2′-C-substituted carbanucleosides

Conformationally restricted 2′-C-azido-, hydroxy- and fluoromethyl-carbanucleosides 4b-f were efficiently synthesized via the stereoselective conversion of ketone 7 to epoxide 14, followed by the stereoselective opening of the epoxide with nucleophiles (O

Stereoselective synthesis of 2′-C-methyl-cyclopropyl-fused carbanucleosides as potential anti-HCV agents

(Chemical Equation Presented) Stereoselective synthesis of 2′-C-methyl-cyclopropyl-fused carbanucleosides was accomplished via stereoselective cyclopropanation, regioselective cleavage of the isopropylidene group, stereoselective Grignard reaction, and cy