915772-83-7Relevant academic research and scientific papers
Synthesis, reactivity and conformational stability of an l-phenylalanine derived oxadiazinanone
Dore, Delvis D.,Burgeson, James R.,Davis, Ryan A.,Hitchcock, Shawn R.
, p. 2386 - 2392 (2006)
An l-phenylalanine derived oxadiazinanone bearing an isopropyl group at the N4-position was prepared and acylated with either hydrocinnamoyl or propanoyl chloride. These oxadiazinanones were utilized in titanium-mediated asymmetric aldol reacti
Synthesis and application of oxadiazines as chiral ligands for the enantioselective addition of diethylzinc to aldehydes
Dean, Melissa A.,Hitchcock, Shawn R.
scheme or table, p. 2471 - 2478 (2011/02/22)
A series of oxadiazines derived from l-phenylalanine bearing phenolic substituents have been synthesized in a multistep, one pot process. This process involves the reaction of a mixed anhydride with a β-hydrazino alcohol, methanesulfonylation of the alcohol moiety, and base induced cyclization. The resultant oxadiazines were employed in the asymmetric addition of diethylzinc to aldehydes.
