915975-60-9Relevant academic research and scientific papers
One-Step Synthesis of the 1-Azaspiro[5.5]undecane Skeleton Characteristic of Histrionicotoxin Alkaloids from Linear Substrates via Hg(OTf)2-Catalyzed Cycloisomerization
Matsumura, Kunihiro,Nishikawa, Keisuke,Yoshida, Hiroaki,Niwa, Toshiki,Fushii, Yuichiro,Doe, Matsumi,Morimoto, Yoshiki
, p. 1882 - 1886 (2021)
Histrionicotoxin (HTX) alkaloids isolated from the poison arrow frogs possess a unique structure characterized by a 1-azaspiro[5.5]undecane skeleton common to the HTX family. The unique molecular architecture of HTXs and the interest as potential target d
The allenic Alder-ene reaction: constitutional group selectivity and its application to the synthesis of ovalicin
Brummond, Kay M.,McCabe, Jamie M.
, p. 10541 - 10554 (2007/10/03)
The scope of the novel allenic Alder-ene reaction using Rh(I) and Ir(I) catalysts has been extended to differentially substituted 1,1,3-trisubstituted allenes. This allenyl substitution pattern can give three possible cross-conjugated triene products. The
