77113-48-5

Basic information

• Product Name: 1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE
• Synonyms: 1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE;(5-chloro-1-pentynyl)trimethylsilylsilane;(5-Chloro-1-pentynyl)trimethylsilane;(5-chloropent-1-yn-1-yl)triMethylsilane;(5-Chloro-1-pentynyl)trimethylsilane 97%;5-chloropent-1-ynyl(trimethyl)silane
• CAS NO: 77113-48-5
• Molecular Formula: C₈H₁₅ClSi
• Molecular Weight: 174.74
• Mol File: 77113-48-5.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 75-77 °C20.6 mm Hg(lit.)
• Flash Point: 149 °F
• Appearance: /
• Density: 0.977 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.44mmHg at 25°C
• Refractive Index: n20/D 1.4560(lit.)
• CAS DataBase Reference: 1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE(77113-48-5)
• EPA Substance Registry System: 1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE(77113-48-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 77113-48-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 77113-48-5 differently. You can refer to the following data:
1. 1-Chloro-5-trimethylsilyl-4-pentyne is used as an organic chemical synthesis intermediate.
2. (5-Chloro-1-pentynyl)trimethylsilane can be used to synthesize 5-trimethylsilyl-4-pentynyllithium (TMSPLi), which can be used as an initiator in the polymerization of styrene.

InChI:InChI=1/C8H15ClSi/c1-10(2,3)8-6-4-5-7-9/h4-5,7H2,1-3H3

Upstream product

• 6940-76-7 1-iodo-3-chloro-propane 
• 1066-54-2 trimethylsilylacetylene 
• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 5390-04-5 pent-1-yn-5-ol 
• 13224-84-5 5-trimethylsilanyl-pent-4-yn-1-ol 
• 75-77-4 chloro-trimethyl-silane 
• 109-70-6 1.3-chlorobromopropane 
• 14267-92-6 1-chloro-4-pentyne 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 

Downstream Products

• 158661-75-7 5-diphenylphosphinopent-1-yne 
• 212913-84-3 Pentadec-14-in-saeure 
• 88564-19-6 2-butyl-3-(4-pentynyl)-2-cyclohexenone 

Relevant articles and documents

Ynonylation of Acyl Radicals by Electroinduced Homolysis of 4-Acyl-1,4-dihydropyridines

Herein we report the conversion of 4-Acyl-1,4-dihydropyridines (DHPs) into ynones under electrochemical conditions. The reaction proceeds via the homolysis of acyl-DHP under electron activation. The resulting acyl radicals react with hypervalent iodine(III) reagents to form the target ynones or ynamides in acceptable yields. This mild reaction condition allows wider functionality tolerance that includes halides, carboxylates, or alkenes. The synthetic utility of this methodology is further demonstrated by the late-stage modification of complex molecules.

Intramolecular anti-Phosphinoauration of Alkynes: An FLP-Motivated Approach to Stable Aurated Phosphindolium Complexes

The synthesis of aurated phosphindolium complexes from easy accessible 1,5-alkynylphosphine derivatives has been studied by using gold(I) complexes featuring carbene and phosphine ligands as initiators. Upon formation of the mixed phosphine NHC/phosphine

Zinc-catalyzed silylation of terminal alkynes

(Chemical Equation Presented) A rapid and high-yielding silylation of terminal alkynes employing TMSOTf and catalytic quantities of Zn(OTf) 2 has been developed. The reaction works well for a variety of substrates including reactive esters. Fifteen examples with yields of >90% are reported.