91600-44-1

Upstream product

• 75-90-1 2,2,2-Trifluoroacetaldehyde 
• 4392-24-9 Cinnamyl bromide 
• 383-63-1 ethyl trifluoroacetate, 
• 19752-27-3 phenylallyl(tributyl)stannane 

Downstream Products

• 867156-70-5 [1-(1-allyloxy-2,2,2-trifluoro-ethyl)-allyl]-benzene 
• 867156-72-7 2-(2-phenyl-1-trifluoromethyl-but-3-enyloxymethyl)-acrylic acid ethyl ester 

Relevant academic research and scientific papers

Zinc bromide promoted allylation of aluminum acetals derived from perfluoro carboxylic acid esters and diisobutylaluminum hydride. New convenient access to α-perfluoroalkylated homoallyl alcohols

The reaction of aluminum acetals, generated in situ by the reduction between perfluoro carboxylic acid esters and diisobutylaluminum hydride, with a variety of allylstannanes efficiently proceeds in the presence of zinc bromide at 40°C to afford the corresponding α-perfluoroalkyl-substituted homoallyl alcohols in good yields.

PREPARATION OF TRIFLUOROMETHYLATED ALLYLIC ALCOHOLS FROM TRIFLUOROACETALDEHYDE AND ORGANOMETALLIC COMPOUNDS

A number of allylic alcohols bearing a trifluoromethyl group at the α- or γ-position, and α-trifluoromethylated γ-enols and -ynols were prepared by the reaction of trifluoroacetaldehyde with a variety of organometallic compounds.Most of the Reformatsky- or Grignard-type reactions required promotion by ultrasonic irradiation.