916154-00-2

Upstream product

• 916153-97-4 allyl 3,5-O-(1-methylethylidene)-α and β-D-xylofuranoside 
• 100-39-0 benzyl bromide 
• 916153-98-5 (4aR,7R,7aS)-6-Allyloxy-7-benzyloxy-2,2-dimethyl-tetrahydro-furo[3,2-d][1,3]dioxine 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 916154-01-3 Benzoic acid (4R,5R)-4-((S)-1-benzyloxy-allyl)-2,2-dimethyl-[1,3]dioxan-5-yl ester 
• 916154-02-4 Benzoic acid (1R,2R,3S)-3-benzyloxy-2-hydroxy-1-hydroxymethyl-pent-4-enyl ester 
• 917096-34-5 (S)-hept-6-en-2-yl (3R,4S,5S)-5-benzyloxy-3-methoxy-4-(4-methoxybenzyloxy)hept-6-enoate 
• 917096-25-4 (3R,4S,5S)-5-benzyloxy-3-methoxy-4-(4-methoxybenzyloxy)hept-6-enoic acid 
• 917096-35-6 (S)-hept-6-en-2-yl (3R,4S,5S)-5-benzyloxy-4-hydroxy-3-methoxyhept-6-enoate 
• 917096-24-3 (S)-hept-6-en-2-yl (3R,5S)-5-benzyloxy-3-methoxy-4-oxohept-6-enoate 
• 917096-32-3 methyl (3R,4S,5S)-5-benzyloxy-3-methoxy-4-(4-methoxybenzyloxy)hept-6-enoate 
• 917096-29-8 5-benzyloxy-4-hydroxy-3-methoxy-hept-6-enoic acid methyl ester 
• 917096-30-1 5-benzyloxy-3-methoxy-4-oxo-hept-6-enoic acid methyl ester 
• 917096-27-6 4-benzyloxy-2-methoxy-hex-5-ene-1,3-diol 
• 917096-28-7 (2S,3R,4S)-4-Benzyloxy-1-iodo-2-methoxy-hex-5-en-3-ol 
• 917096-26-5 4-(1-benzyloxy-allyl)-5-methoxy-2,2-dimethyl-[1,3]dioxane 

Relevant academic research and scientific papers

The first total synthesis of sporiolide B

The first total synthesis of natural cytotoxic agent, sporiolide B, is described. d-Xylose was used as the chiral template to pre-control the absolute configuration during the synthesis. Yamaguchi esterification and ring closing metathesis greatly facilit

The first total synthesis of sporiolide A

The first total synthesis of the natural cytotoxic agent sporiolide A has been accomplished from D-glucal in 16 steps with 6.1% overall yield. Carbohydrates were applied as the chiral templates to manipulate the absolute configuration during the synthesis