916159-69-8

Upstream product

• 117168-59-9 (2S,3S,4R)-2-azido-1,3,4-octadecanetriol 
• 554-62-1 D-ribo-phytosphingosine 
• 916159-68-7 (2S,3S,4R)-2-azido-1-(tert-butyldiphenylsilyloxy)octadecane-3,4-diol 

Downstream Products

• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 103348-49-8 2-azido-sphingosine 
• 109785-20-8 O-(β-D-galactopyranosyl)-(1→4)-(β-D-glucopyranosyl)-(1→1)-(2S, 3R, 4E)-2-aminooctadec-4-ene-1,3-diol 
• 1313734-16-5 (R)-2-(1R,2S)-2-azido-3-(tert-butyldiphenylsilyloxy-1-hydroxypropyl)hexadecanitrile 
• 1313734-22-3 C₄₁H₇₁NO₂Si₂ 
• 1313734-21-2 C₄₁H₆₉NO₃Si₂ 
• 1313734-20-1 C₄₁H₇₁N₃O₃Si₂ 
• 1313734-19-8 (S)-2-((5R,6S)-6-azido-2,2,3,3,10,10-hexamethyl-9,9-diphenyl-4,8-dioxa-3,9-disilaundecan-5-yl)hexadecanoic acid 
• 1313734-18-7 C₄₁H₆₉N₃O₃Si₂ 
• 1313734-17-6 C₄₁H₆₈N₄O₂Si₂ 
• 916159-71-2 (2S,3S,4S)-2-azido-1-(tert-butyldiphenylsilyloxy)-4-iodooctadecan-3-ol 
• 916159-70-1 (2S,3R)-(E)-2-azido-1-(tert-butyldiphenylsilyloxy)octadec-4-en-3-ol 
• 1571918-48-3 N-((2R,3R,E)-3-hydroxy-1-((2-(hydroxymethyl)phenyl)thio)-octadec-4-en-2-yl)octanamide 
• 1571918-47-2 N-((2R,3R,E)-1-((2-(hydroxymethyl)phenyl)thio)-3-(methoxymethoxy)octadec-4-en-2-yl) octanamide 

Relevant academic research and scientific papers

Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens

A highly efficient streamlined chemoenzymatic strategy for total synthesis of four prioritized ganglioside cancer antigens GD2, GD3, fucosyl GM1, and GM3 from commercially available lactose and phytosphingosine is demonstrated. Lactosyl sphingosine (LacβS

Chemoenzymatic synthesis and biological evaluation of ganglioside GM3 and lyso-GM3 as potential agents for cancer therapy

A highly efficient chemoenzymatic method for synthesizing ganglioside GM3 and lyso-GM3 was reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient one-pot multienzyme (OPME) reaction allowed glycosylation to b

Ganglioside GM3 and/or analogue thereof, synthesis method and application of ganglioside GM3 and/or analogue thereof

The invention relates to a method for synthesizing ganglioside GM3 and/or an analogue thereof. The method includes the following steps: (1) selecting a lactose donor represented by a general formula Iand/or an analogue thereof and selecting a sphingosine

Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer

A highly efficient chemoenzymatic method for synthesizing glycosphingolipids using α-Gal pentasaccharyl ceramide as an example is reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient sequential one-pot mult

Efficient synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine via a cyclic sulfate intermediate

The synthesis of naturally occurring D-erythro-sphingosine and synthetically useful D-erythro-2-azidosphingosine from commercially available D-ribo-phytosphingosine is described. An important feature of this synthesis is the selective transformation of the 3,4-vicinal diol of phytosphingosine into the characteristic E-allylic alcohol of sphingosine via a cyclic sulfate intermediate.