916159-70-1

Upstream product

• 117168-59-9 (2S,3S,4R)-2-azido-1,3,4-octadecanetriol 
• 114275-40-0 (2R,3R)-trans-2-azide-1,3-O-benzylidene-1,3-octadec-4-enediol 
• 114275-39-7 (2R,3R,4E)-1,3-benzylidene-4-octadecene-1,2,3-triol 
• 3006-41-5 4,6-O-benzylidene-α,β-D-galactopyranose 
• 10257-28-0 D-Galactose 
• 554-62-1 D-ribo-phytosphingosine 
• 916159-68-7 (2S,3S,4R)-2-azido-1-(tert-butyldiphenylsilyloxy)octadecane-3,4-diol 
• 916159-69-8 [(S)-2-azido-2-((4S,5R)-2,2-dioxo-5-tetradecyl-2λ⁶-[1,3,2]dioxathiolan-4-yl)ethoxy]-tert-butyldiphenylsilane 

Downstream Products

• 103348-50-1 (2S,3R,4E)-2-azido-3-benzoyloxy-4-octadecen-1-ol 
• 1416052-09-9 (2S,3R,4E)-2-amino-3-O-(tert-butyldimethylsilyl)-1-O-(tert-butyldiphenylsilyl)octadec-4-ene-1,3-diol 
• 1416052-10-2 (2S,3R,4E)-2-[(30'-acetoxy)triacontanamido]-3-O-(tert-butyldimethylsilyl)-1-O-(tert-butyldiphenylsilyl)octadec-4-ene-1,3-diol 
• 1416052-11-3 (2S,3R,4E)-3-O-(tert-butyldimethylsilyl)-1-O-(tert-butyldiphenylsilyl)-2-[(30'-hydroxy)triacontanamido]octadec-4-ene-1,3-diol 
• 1416052-13-5 (2S,3R,4E)-3-O-(tert-butyldimethylsilyl)-1-O-(tert-butyldiphenylsilyl)-2-[(30'-stearoyloxy)triacontanamido]octadec-4-ene-1,3-diol 
• 1416052-08-8 (2S,3R,4E)-2-azido-3-O-(tert-butyldimethylsilyl)-1-O-(tert-butyldiphenylsilyl)octadec-4-ene-1,3-diol 
• 1571919-07-7 N-((2S,3R,E)-1-(benzyl(2-hydroxyethyl)amino)-3-(methoxymethoxy)octadec-4-en-2-yl) octanamide 
• 1571919-08-8 N-((2S,3R,E)-1-(benzyl(2-hydroxyethyl)amino)-3-hydroxyoctadec-4-en-2-yl)octanamide 
• 1571918-45-0 N-((2R,3R,E)-3-(methoxymethoxy)-1-(phenylthio)octadec-4-en-2-yl)octanamide 
• 1571918-46-1 N-((2R,3R,E)-3-hydroxy-1-(phenylthio)octadec-4-en-2-yl)-octanamide 
• 1571918-47-2 N-((2R,3R,E)-1-((2-(hydroxymethyl)phenyl)thio)-3-(methoxymethoxy)octadec-4-en-2-yl) octanamide 
• 1571918-48-3 N-((2R,3R,E)-3-hydroxy-1-((2-(hydroxymethyl)phenyl)thio)-octadec-4-en-2-yl)octanamide 
• 1571918-33-6 (2S,3R,E)-2-azido-1-((tert-butyldiphenylsilyl)oxy)-3-(methoxymethoxy)octadec-4-en 
• 2238-90-6 psychosine 

Relevant academic research and scientific papers

Chemoenzymatic synthesis and biological evaluation of ganglioside GM3 and lyso-GM3 as potential agents for cancer therapy

A highly efficient chemoenzymatic method for synthesizing ganglioside GM3 and lyso-GM3 was reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient one-pot multienzyme (OPME) reaction allowed glycosylation to b

Ganglioside GM3 and/or analogue thereof, synthesis method and application of ganglioside GM3 and/or analogue thereof

The invention relates to a method for synthesizing ganglioside GM3 and/or an analogue thereof. The method includes the following steps: (1) selecting a lactose donor represented by a general formula Iand/or an analogue thereof and selecting a sphingosine

An Improved, Versatile, and Easily Scalable Synthesis of Sphingomyelins: Application to Stable Isotope Labeling

With a view to make conveniently labeled mass spectrometry standards available, a set of deuterated sphingomyelins were prepared by a new expedient, flexible, robust, scalable, and high-yielding synthetic scheme starting from 2-azido-3- O -benzoylsphingos

Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens

A highly efficient streamlined chemoenzymatic strategy for total synthesis of four prioritized ganglioside cancer antigens GD2, GD3, fucosyl GM1, and GM3 from commercially available lactose and phytosphingosine is demonstrated. Lactosyl sphingosine (LacβS

Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer

A highly efficient chemoenzymatic method for synthesizing glycosphingolipids using α-Gal pentasaccharyl ceramide as an example is reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient sequential one-pot mult

Aziridine ring opening for the synthesis of sphingolipid analogues: Inhibitors of sphingolipid-metabolizing enzymes

A library of sphingolipid analogues is designed and tested as inhibitors against mammalian and fungal sphingolipid enzymes. The synthesis of sphingolipid analogues is based on the nucleophilic ring-opening reactions of N-activated aziridine derivatives wi

Efficient synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine via a cyclic sulfate intermediate

The synthesis of naturally occurring D-erythro-sphingosine and synthetically useful D-erythro-2-azidosphingosine from commercially available D-ribo-phytosphingosine is described. An important feature of this synthesis is the selective transformation of the 3,4-vicinal diol of phytosphingosine into the characteristic E-allylic alcohol of sphingosine via a cyclic sulfate intermediate.