916176-52-8

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Bromo-5-chloro-7-aza-1H-indole is used as a key intermediate in the synthesis of various pharmaceuticals for its potential biological activities. Its unique structure and functional groups make it a valuable building block for developing new drugs with specific therapeutic properties.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4-Bromo-5-chloro-7-aza-1H-indole is employed as a precursor in the development of novel agrochemicals. Its antimicrobial and antiproliferative properties contribute to the creation of effective agents for pest control and crop protection.
Used in Drug Development:
4-Bromo-5-chloro-7-aza-1H-indole is utilized in drug development due to its reported antimicrobial and antiproliferative properties. These characteristics make it a promising candidate for the discovery of new therapeutic agents, particularly in the treatment of infectious diseases and cancer.
Used as a Building Block for Organic Synthesis:
4-Bromo-5-chloro-7-aza-1H-indole may also serve as a versatile building block for the synthesis of other complex organic molecules. Its unique structure and functional groups can be further modified or combined with other chemical entities to create new compounds with diverse applications in various fields.

Upstream product

• 866546-07-8 5-chloro-1H-pyrrolo[2,3-b]pyridine 
• 916176-51-7 5-chloro-1H-pyrrolo[2.3-b]pyridine oxide 

Downstream Products

• 916176-53-9 4-bromo-5-chloro-1-p-toluenesulfonyl-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

Substituted heteroaryl compound and composition and application thereof

The invention provides a substituted heteroaryl compound and a pharmaceutical composition and application thereof. The compound is a compound as shown in formula (I) or the stereisomer, tautomer, nitric oxide, solvate, metabolite, pharmaceutically acceptable salt or prodrug of the compound as shown in formula (I). The pharmaceutical composition containing the compound can regulate the activity ofprotein kinase and especially the activity of Aurora kinase and JAK kinase and is used for preventing, treating and relieving diseases or disorder mediated by protein kinase and especially JAK kinase.

SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASE

The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in

PYRROLOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASE

The present invention relates to compounds of formula (I) wherein Q, Z, R1 , R2 , and R3 are as described in claim 1 useful as inhibitors of protein kinases, particularly of JAK family and ROCK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.