916210-98-5 Usage
Uses
Used in Pharmaceutical Industry:
(2-Chloropyridin-4-yl)methanamine hydrochloride is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of biologically active substances. It plays a crucial role in the production of drugs, enhancing their efficacy and therapeutic potential.
Used in Agrochemical Industry:
In the agrochemical sector, (2-Chloropyridin-4-yl)methanamine hydrochloride is utilized as a building block in the synthesis of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Research and Development:
(2-Chloropyridin-4-yl)methanamine hydrochloride is employed as a valuable research tool in the pharmaceutical industry, aiding in the discovery and optimization of new drug candidates through its versatile chemical properties and reactivity.
Used in Organic Compound Synthesis:
(2-Chloropyridin-4-yl)methanamine hydrochloride is also used as a starting material in the synthesis of various organic compounds, broadening its applications across different chemical and industrial fields.
Check Digit Verification of cas no
The CAS Registry Mumber 916210-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,2,1 and 0 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 916210-98:
(8*9)+(7*1)+(6*6)+(5*2)+(4*1)+(3*0)+(2*9)+(1*8)=155
155 % 10 = 5
So 916210-98-5 is a valid CAS Registry Number.
916210-98-5Relevant academic research and scientific papers
Weber, Stefan,Veiros, Luis F.,Kirchner, Karl
, p. 5412 - 5420 (2019)
An efficient additive-free manganese-catalyzed hydrogenation of nitriles to primary amines with molecular hydrogen is described. The pre-catalyst, a well-defined bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dpre)(CO)3(CH3)] (dpre=1,2-bis(di-n-propylphosphino)ethane), undergoes CO migratory insertion into the manganese-alkyl bond to form acyl complexes which upon hydrogenolysis yields the active coordinatively unsaturated Mn(I) hydride catalyst [Mn(dpre)(CO)2(H)]. A range of aromatic and aliphatic nitriles were efficiently and selectively converted into primary amines in good to excellent yields. The hydrogenation of nitriles proceeds at 100 °C with a catalyst loading of 2 mol % and a hydrogen pressure of 50 bar. Mechanistic insights are provided by means of DFT calculations. (Figure presented.).
