916248-91-4Relevant academic research and scientific papers
Synthesis and biological evaluation of novel pyrazolopyrimidines derivatives as anticancer and anti-5-lipoxygenase agents
Rahmouni, Ameur,Souiei, Sawssen,Belkacem, Mohamed Amine,Romdhane, Anis,Bouajila, Jalloul,Ben Jannet, Hichem
, p. 160 - 168 (2016)
A novel series of 6-Aryl-3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones 3a-h were synthesized in a single step via condensation of carboxamide 2 with some aromatic aldehydes (presence of iodine). Treatment of aminopyrazole 1a with acetic anhydri
Microwave synthesis of new pyrazolo[3,4-d]pyrimidin-4-ones in solvent-free condition
Davoodnia,Anvari,Tavakoli-Hoseini
experimental part, p. 3683 - 3685 (2012/02/06)
An efficient method for the synthesis of new pyrazolo[3,4-d]pyrimidin-4- ones through heterocyclization reaction of 5-amino-l-phenyl- lH-pyrazole-4-carboxamides with aroyl halides under microwave irradiation in solvent-free condition is described. In comparison with classical conditions the reactions are faster and the yields are higher under microwave irradiation.
