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Upstream product

• 4654-39-1 4-bromophenethanol 
• 98-88-4 benzoyl chloride 
• 120-46-7 1,3-diphenylpropanedione 

Downstream Products

• 1403599-74-5 C₁₅H₁₃⁽¹⁸⁾FO₂ 
• 326-46-5 2-(4-fluorophenyl)ethyl benzoate 

Relevant academic research and scientific papers

Cu-catalyzed esterification reaction via aerobic oxygenation and C-C bond cleavage: An approach to α-ketoesters

The Cu-catalyzed novel aerobic oxidative esterification reaction of 1,3-diones for the synthesis of α-ketoesters has been developed. This method combines C-C σ-bond cleavage, dioxygen activation and oxidative C-H bond functionalization, as well as provides a practical, neutral, and mild synthetic approach to α-ketoesters which are important units in many biologically active compounds and useful precursors in a variety of functional group transformations. A plausible radical process is proposed on the basis of mechanistic studies.

Nickel-mediated oxidative fluorination for PET with aqueous [ 18F] fluoride

A one-step oxidative fluorination for carbon-fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical 18F late-stage fluorination of complex small molecules with potential for PET imaging.