91641-04-2Relevant academic research and scientific papers
Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity
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, (2008/06/13)
This invention provides a novel oxyiminoalkanoic acid derivative which has excellent hypoglycemic and hypolipidemic actions and which is used for the treatment of diabetes mellitus, hyperlipemia, insulin insensitivity, insulin resistance and impaired glucose tolerance.
6-Phenyl-6-alkylamido-5,6-dihydro-2H-pyran-2-ones: Novel HIV protease inhibitors
Hamilton, Harriet W.,Tait, Bradley D.,Gajda, Christopher,Hagen, Susan E.,Ferguson, Donna,Lunney, Elizabeth A.,Pavlovsky, Alexander,Tummino, Peter J.
, p. 719 - 724 (2007/10/03)
Publications from our laboratories have recently described a series of 3-thioaryl substituted-4-hydroxy-pyrones as HIV protease inhibitors. The current work examines the analogues 5,6-dihydro-2H-pyran-2-ones with 6,6-substitutions focusing on the use of 1
