916433-72-2Relevant academic research and scientific papers
Highly convergent three component benzyne coupling: The total synthesis of ent-clavilactone B
Larrosa, Igor,Da Silva, Marianne I.,Gomez, Patricio M.,Hannen, Peter,Ko, Eunjung,Lenger, Steven R.,Linke, Simon R.,White, Andrew J. P.,Wilton, Donna,Barrett, Anthony G. M.
, p. 14042 - 14043 (2007/10/03)
The first total synthesis of (+)-clavilactone B, a potent antifungal agent and novel tyrosine kinase inhibitor, is described. The absolute configuration of clavilactones has been unambiguously established by using Sharpless asymmetric epoxidation to gener
