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1-(2-METHANESULFONYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE is a chemical compound that belongs to the class of piperazine derivatives. It is a dihydrochloride salt of the piperazine compound, which is commonly used in the synthesis of pharmaceuticals and drugs. 1-(2-METHANESULFONYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE features a piperazine ring with a methanesulfonyl-phenyl substituent at the 1 position, and it is present in the form of a dihydrochloride salt, which enhances its stability and suitability for pharmaceutical applications. The chemical may possess various pharmacological properties and could be utilized in the treatment of certain medical conditions, with its specific uses and effects depending on the context and formulation in which it is employed.

916488-42-1

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916488-42-1 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-METHANESULFONYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE is used as a key intermediate in the synthesis of various pharmaceuticals and drugs for its potential pharmacological properties. Its specific role in drug development would be determined by the therapeutic target and the formulation in which it is incorporated.

Check Digit Verification of cas no

The CAS Registry Mumber 916488-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,4,8 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 916488-42:
(8*9)+(7*1)+(6*6)+(5*4)+(4*8)+(3*8)+(2*4)+(1*2)=201
201 % 10 = 1
So 916488-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O2S.ClH/c1-16(14,15)11-5-3-2-4-10(11)13-8-6-12-7-9-13;/h2-5,12H,6-9H2,1H3;1H

916488-42-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-methylsulfonylphenyl)piperazine,hydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:916488-42-1 SDS

916488-42-1Downstream Products

916488-42-1Relevant academic research and scientific papers

Novel potent neuropeptide Y Y5 receptor antagonists: Synthesis and structure-activity relationships of phenylpiperazine derivatives

Takahashi, Toshiyuki,Sakuraba, Aya,Hirohashi, Tomoko,Shibata, Takunobu,Hirose, Masaaki,Haga, Yuji,Nonoshita, Katsumasa,Kanno, Tetsuya,Ito, Junko,Iwaasa, Hisashi,Kanatani, Akio,Fukami, Takehiro,Sato, Nagaaki

, p. 7501 - 7511 (2007/10/03)

A series of phenylpiperazine derivatives were synthesized and evaluated for their neuropeptide Y (NPY) Y5 receptor antagonistic activities. The benzindane portion of 2 was replaced by 1-phenylpiperazine, resulting in novel urea derivative 3f. Subsequent optimization of the phenylpiperazine template by substitution of the phenyl moiety resulted in a series of (2-methanesulfonamidephenyl)piperazine derivatives that showed potent binding affinity and antagonistic activity for the Y5 receptor.

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