916598-58-8

Basic information

• Product Name: Glycine, N-[2-(3,4-dimethoxyphenyl)ethyl]-, 2-propen-1-yl ester
• CAS NO: 916598-58-8
• Molecular Formula: C15H21NO4
• Molecular Weight: 279.336
• Mol File: 916598-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Glycine, N-[2-(3,4-dimethoxyphenyl)ethyl]-, 2-propen-1-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[2-(3,4-dimethoxyphenyl)ethyl]-, 2-propen-1-yl ester(916598-58-8)
• EPA Substance Registry System: Glycine, N-[2-(3,4-dimethoxyphenyl)ethyl]-, 2-propen-1-yl ester(916598-58-8)

Safety Data

• Hazardous Substances Data: 916598-58-8(Hazardous Substances Data)

Upstream product

• 40630-84-0 allyl bromoacetate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 916598-60-2 N-[(9H-fluorenyl-9-ylmethoxy)carbonyl]-L-alanyl-N-(3,4-dimethoxyphenethyl)glycine allyl ester 

Relevant articles and documents

Hydrazone- and hydrazide-containing N-substituted glycines as peptoid surrogates for expedited library synthesis: Application to the preparation of Tsg101-directed HIV-1 budding antagonists

(Chemical Equation Presented) Replacing the Pro6 in the p6 Gag-derived 9-mer "P-E-P-T-A-P-P-E-E" with N-substituted glycine (NSG) residues is problematic. However, incorporation of hydrazone amides ("peptoid hydrazones") can be readily achieved in library fashion. Furthermore, reduction of these hydrazones to N-substituted "peptoid hydrazides" affords a facile route to library diversification. This approach is demonstrated by application to Tsg101-binding compounds designed as potential HIV budding antagonists.