916653-64-0Relevant academic research and scientific papers
Sulfonamide ligands attained through opening of saccharin derivatives
Robinson, Richard I.,Fryatt, Ross,Wilson, Claire,Woodward, Simon
, p. 4483 - 4489 (2007/10/03)
Literature N-alkylsaccharins (saccharin-R2) have been shown in some cases to be O-alkylated regioisomers by crystallography (3 structures). The genuine former species react with (S)-H2NCHR1CH 2OH at 101°C in dio
Sulfonic acid libraries attained through opening of 2-sulfobenzoic acid anhydride
Robinson, Richard I.,Stephens, John C.,Worden, Steve M.,Blake, Alexander J.,Wilson, Claire,Woodward, Simon
, p. 4596 - 4605 (2007/10/03)
2-Sulfobenzoic acid anhydride opens cleanly with N-Boc-protected α-amino alcohols to afford zwitterionic esters 1,2-C6H 4(SO3-)(CO2CH2CHR 1NH3+) (R1/s
