916675-58-6Relevant academic research and scientific papers
Side-bridged cyclam transition metal complexes bearing a phenolic ether or a phenolate pendent arm
Mewis, Ryan E.,Archibald, Stephen J.
, p. 578 - 589 (2019/09/03)
Side-bridged cyclam transition metal complexes (M = Ni(II), Cu(II) and Zn(II)) bearing a phenolic ether or phenolate pendent arm have been synthesised. For [NiL1]+ and [CuL1]+, evidence for a phenoxyl radical wa
Synthesis and structural characterization of a highly substituted triazine ring comprising a sterically flexible methylene linker and coordinating substituents
Werlé, Christophe,Yin, Chih-Juo Madeline,Heinemann, Frank W.,Hauser, Christina,Meyer, Karsten
, p. 2715 - 2719 (2017/06/23)
The efficient multi-step, large-scale synthesis, spectroscopic characterization and solid-state molecular structure of a new type of three-fold functionalized, sterically demanding triazine is reported. The aromatic heterocycle 6,6′,6′'-((1,3,5-triazine-2,4,6-triyl)tris(methylene))tris(2,4-di-tert-butylphenol) possesses three 2,4-di-tert-butylphenol synthons bound to the 1,3,5-triazine ring via synthetically challenging methylene linkages in the 2,4,6 positions. The key to success was found in the generation of a highly reactive imidate hydrochloride salt, namely ethyl 2-(3,5-di-tert-butyl-2-methoxyphenyl)acetimidate hydrochloride, that readily undergoes cyclotrimerization. The reported preparation opens new perspectives in the design and synthesis of novel triazine molecules bearing flexible and sterically demanding functionalized groups for various applications.
Visible-Light-Induced Cyclization of Electron-Enriched Phenyl Benzyl Sulfides: Synthesis of Tetrahydrofurans and Tetrahydropyrans
Li, Wei,Yang, Chao,Gao, Guo-Lin,Xia, Wujiong
supporting information, p. 1391 - 1396 (2016/06/01)
A new approach to the preparation of tetrahydrofurans and tetrahydropyrans through a photoredox catalytic process is described. The introduction of a phenylsulfanyl auxiliary group permits the substrates to be readily oxidized to form cationic intermediates for sequential intramolecular cyclization. The method features mild reaction conditions and operational simplicity.
Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process
Tummatorn, Jumreang,Thongsornkleeb, Charnsak,Ruchirawat, Somsak,Gettongsong, Tanita
supporting information, p. 1463 - 1467 (2013/05/08)
A convenient synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters via a domino process is described. The synthesis employs arylmethyl azides as the precursor which undergoes an acid-promoted rearrangement to give an N-aryl iminium ion. Following the addition with ethyl 3-ethoxyacrylate, intramolecular electrophilic aromatic substitution, elimination and subsequent oxidation, the quinoline products were obtained in moderate to excellent yields.
Synthesis of differently substituted tacn-based ligands: Towards the control of solubility and electronic and steric properties of uranium coordination complexes
Nizovtsev, Alexey V.,Scheurer, Andreas,Kosog, Boris,Heinemann, Frank W.,Meyer, Karsten
, p. 2538 - 2548 (2013/07/11)
Starting from phenols R1,R2ArOH (5) and the anisole derivative 3,5-di-tert-butyl-2-methoxybenzyl bromide (13), a series of new tacn-based ligands (R1,R2ArOR3)3tacn (2) have been synthesized with substituents of
Efficient synthesis of 2-substituted imidazoles by palladium-catalyzed cross-coupling with benzylzinc reagents
Utas, Josefin E.,Olofsson, Berit,?kermark, Bj?rn
, p. 1965 - 1967 (2008/02/08)
Substituted benzylzinc reagents have been used in novel cross-coupling reactions with 2-iodo imidazoles to form compounds containing both a phenol and an imidazole moiety. The intramolecular hydrogen-bonding properties of these compounds were subsequently studied. Georg Thieme Verlag Stuttgart.
