916755-45-8Relevant academic research and scientific papers
Synthesis of new camptothecin analogues with the E-lactone ring replaced by α,β-cyclohexenone
Bacherikov, Valeriy A.,Tsai, Tsong-Jen,Chang, Jang-Yang,Chou, Ting-Chao,Lee, Rong-Zau,Su, Tsann-Long
, p. 4490 - 4499 (2006)
The total synthesis of racemic camptothecin analogues 12a and 12b, in which the E-lactone ring has been replaced by an α,β-cyclohexenone ring and the ethyl and hydroxy substituents have been retained, was achieved by first preparing the ABCD fragments 31a
