916843-52-2

Upstream product

• 916843-43-1 (S)-allyl N-[1-(4-methoxybenzyloxy)-4-(trifluoromethyl)pent-4-en-2-yl]-N-(4-methylbenzenesulfonyl)carbamate 
• 916843-46-4 (S)-N-[1-(4-methoxybenzyloxy)-4-(trifluoromethyl)pent-4-en-2-yl]-4-methylbenzenesulfonamide 
• 884487-63-2 (R)-1-(4-methoxybenzyloxy)-4-(trifluoromethyl)pent-4-en-2-ol 
• 916843-50-0 (S)-4-difluoromethylene-2-[(4-methoxybenzyloxy)methyl]-1-(4-methylbenzenesulfonyl)pyrrolidine 

Relevant academic research and scientific papers

Divergent chemical synthesis of prolines bearing fluorinated one-carbon units at the 4-position via nucleophilic 5-endo-trig cyclizations

N-[3-(Trifluoromethyl)homoallyl]sulfonamides, prepared via ring opening of (5)-glycidyl ethers or 2-aryloxiranes with 1-(trifluoromethyl)vinyllithium, underwent intramolecular addition or SN2′-type reaction in the normally disfavored 5-endo-tri