916907-11-4

Basic information

• Product Name: 4-(2,6-dichlorophenyl)-4-hydroxy-8-methylsulfanyl-1,2,4,5-tetrahydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one
• CAS NO: 916907-11-4
• Molecular Weight: 397.285
• Mol File: 916907-11-4.mol

Chemical Properties

• CAS DataBase Reference: 4-(2,6-dichlorophenyl)-4-hydroxy-8-methylsulfanyl-1,2,4,5-tetrahydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,6-dichlorophenyl)-4-hydroxy-8-methylsulfanyl-1,2,4,5-tetrahydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one(916907-11-4)
• EPA Substance Registry System: 4-(2,6-dichlorophenyl)-4-hydroxy-8-methylsulfanyl-1,2,4,5-tetrahydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one(916907-11-4)

Safety Data

• Hazardous Substances Data: 916907-11-4(Hazardous Substances Data)

Upstream product

• 909095-78-9 1-{5-[2-(2,6-dichlorophenyl)-3-oxoethyl]-2-methylsulfanylpyrimidin-4-yl}pyrazolidin-3-one 
• 909095-74-5 5-bromomethyl-4-chloro-2-(methylthio)pyrimidine 
• 909095-75-6 2-(4-chloro-2-methylsulfanylpyrimidin-5-yl)-1-(2,6-dichlorophenyl)ethanone 
• 61044-96-0 4-chloro-5-methyl-2-(methylsulfanyl)pyrimidine 

Downstream Products

• 909095-79-0 4-(2,6-dichlorophenyl)-8-methylsulfanyl-1,2-dihydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one 
• 909095-82-5 4-(2,6-dichlorophenyl)-8-methylsulfinyl-1,2-dihydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one 

Relevant articles and documents

Synthesis of novel pyrimido[4,5-c]pyridazines and 1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-ones as potent inhibitors of lymphocyte specific kinase (LCK)

This paper details the synthesis of a novel class of 1,2-dihydro-pyrimido[4,5-c]pyridazines and substituted 1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-one. The most potent analogs disclosed showed low nanomolar activity for the inhibition of