916914-98-2

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 3132-99-8 m-bromobenzoic aldehyde 
• 497065-79-9 (E)-(2R,3R)-2-Amino-3-(dimethyl-phenyl-silanyl)-hex-4-enoic acid methyl ester 

Downstream Products

• 916915-03-2 methyl (2S,5R,6R)-6-(3-bromophenyl)-5-methylpiperidine-2-carboxylate 
• 916914-58-4 (2S,5R,6R)-5-methyl-6-(3-morpholinophenyl)piperidine-2-carboxylic acid 
• 1027921-30-7 (2S,5R,6R)-5-Methyl-6-(3-morpholin-4-yl-phenyl)-piperidine-2-carboxylic acid methyl ester 
• 936445-13-5 (3R,6R,7R,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 936445-12-4 (3S,6R,7R,9aS)-3-(azidomethyl)-6-(3-bromophenyl)-7-methyl-hexahydropyrido[2,1-c][1,4]oxazin-1(6H)-one 
• 916915-01-0 (2S,5R,6R)-6-(3-Bromo-phenyl)-5-methyl-1-(2,2,2-trifluoro-acetyl)-piperidine-2-carboxylic acid methyl ester 
• 916914-57-3 (2S,5R,6R)-6-(3-bromophenyl)-5-methylpiperidine-2-carboxylic acid 

Relevant academic research and scientific papers

Stereochemical and skeletal diversity employing pipecolate ester scaffolds

Equation presented The stereocontrolled synthesis of pyridooxazinones by Mg(OTf)2-promoted epoxide ring-opening with use of chiral pipecolates as nucleophiles is described. Pyridooxazinone products derived from azido-epoxides can be further rea

Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets

A convergent approach to highly functionalized diketopiperazines (DKPs) using enantioenriched pipecolic acids is described. Scandium triflate-catalyzed [4 + 2] aza-annulation was employed to produce stereochemically well-defined building blocks. A resin "