916991-93-0

Upstream product

• 3308-98-3 2-(3-chloropropyl)-2-phenyl-[1,3]dioxolane 
• 68-94-0 hypoxanthine 
• 255824-80-7 2-(2-chloroethyl)-2-phenyl-1,3-dioxolane 
• 936-59-4 3-chloropropiophenone 
• 71-43-2 benzene 
• 939-52-6 4-chloro-1-phenylbutan-1-one 

Relevant academic research and scientific papers

The synthesis of ω-(2-aryl-1,3-dioxolan-2-yl)alkyl purine derivatives and their activity towards HIV reverse transcriptase

Novel derivatives of 6-substituted purines were synthesized by alkylation of 6-substituted purines with various 2-(chloroalkyl)-2-aryl-1,3-dioxolanes and related compounds. Their inhibitory properties toward HIV reverse transcriptase were studied. The structure-activity relationship within the synthesized compounds was found.

Polymethylene derivatives of nucleic bases with ω-functional groups: V. Pyrimidine- and purine-containing γ-butyrophenones

New polymethylene derivatives of nucleic bases containing a keto function in the ω-position were synthesized by alkylation of nucleic bases with 2-(3-chloropropyl)-2-phenyl-1,3-dioxolane and the subsequent deblocking of the keto group; their physicochemical properties were studied.