91703-94-5

Basic information

• Product Name: 9-(2,3,5-tri-O-benzoyl-β-L-ribofuranosyl)-N-palmitoylguanosine
• CAS NO: 91703-94-5
• Molecular Weight: 833.982
• Mol File: 91703-94-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9-(2,3,5-tri-O-benzoyl-β-L-ribofuranosyl)-N-palmitoylguanosine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2,3,5-tri-O-benzoyl-β-L-ribofuranosyl)-N-palmitoylguanosine(91703-94-5)
• EPA Substance Registry System: 9-(2,3,5-tri-O-benzoyl-β-L-ribofuranosyl)-N-palmitoylguanosine(91703-94-5)

Safety Data

• Hazardous Substances Data: 91703-94-5(Hazardous Substances Data)

Upstream product

• 112-67-4 n-hexadecanoyl chloride 
• 73-40-5 guanine 
• 20074-49-1 β-L-arabinofuranoside 
• 21047-87-0 N-palmitoylguanine 
• 41546-19-4 α-L-lyxose 
• 21047-87-0 N²-palmytoylguanine 
• 3080-30-6 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 
• 91703-93-4 Hexadecanoic acid (9-trimethylsilanyl-6-trimethylsilanyloxy-9H-purin-2-yl)-amide 

Downstream Products

• 109923-84-4 Hexadecanoic acid {9-((2S,3S,3aR,9aS)-3-hydroxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-6-[2-(4-nitro-phenyl)-ethoxy]-9H-purin-2-yl}-amide 
• 109923-77-5 9-<2,3,5-tri-O-benzoyl-β-L-ribofuranosyl>-N-palmitoyl-O-6-<(4-nitrophenyl)ethyl>guanosine 

Relevant articles and documents

Chirally-modified oligonucleotides and the control of gene expression. The case of L-DNAs and -RNAs

The affinity of L-DNAs, L-RNAs and LD-DNAs for homopurine · homopyrimidine d.s. D-DNA and s.s. D-RNA was probed by gel electrophoresis and CD spectroscopy. It was found that the L-modified oligomers do not bind to d.s. DNA and to natural RNA that contains all four natural bases. Thus they cannot be used, in general, for the control of gene expression according to the antigene and antisense methodologies. Heterochiral complexes with 1:1 stoichiometry and low hem stability are formed, instead, by homopurinic L- RNA or L/D-DNA and homopyrimidinic L-RNA with the W/C complementary natural RNA sequences.