917247-89-3

Basic information

• Product Name: rac-2-hydroxy-4-(4-fluorophenyl)butanoic acid
• CAS NO: 917247-89-3
• Molecular Weight: 198.194
• Mol File: 917247-89-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-2-hydroxy-4-(4-fluorophenyl)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: rac-2-hydroxy-4-(4-fluorophenyl)butanoic acid(917247-89-3)
• EPA Substance Registry System: rac-2-hydroxy-4-(4-fluorophenyl)butanoic acid(917247-89-3)

Safety Data

• Hazardous Substances Data: 917247-89-3(Hazardous Substances Data)

Upstream product

• 702-15-8 3-(4-fluorophenyl)propan-1-ol 
• 459-57-4 4-fluorobenzaldehyde 
• 63416-70-6 3-(4-fluorophenyl)propanal 
• 136265-10-6 ethyl 4-fluorocinnamate 
• 7116-38-3 ethyl 3-(4-fluorophenyl)propanoate 
• 225233-79-4 rac-2-amino-4-(4-fluorophenyl)butanoic acid 
• 114990-93-1 (S)-2-hydroxy-4-(4-fluorophenyl)butanoic acid 

Downstream Products

• 114990-93-1 (R)-2-hydroxy-4-(4-fluorophenyl)butanoic acid 

Relevant articles and documents

Biocatalytic racemization of (hetero)aryl-aliphatic α- hydroxycarboxylic acids by Lactobacillus spp. proceeds via an oxidation-reduction sequence

The biocatalytic racemization of a range of (hetero)aryl- and (di)aryl-aliphatic α-hydroxycarboxylic acids has been achieved by using whole resting cells of Lactobacillus spp. The essentially mild (physiological) reaction conditions ensure the suppression of undesired side reactions, such as elimination, decomposition or condensation. Cofactor/inhibitor studies using a cell-free extract of Lactobacillus paracasei DSM 20207 reveal that the addition of redox cofactors (NAD+/NADH) leads to a distinct increase in the racemization rate, while strong inhibition is observed in the presence of Thio-NAD+, which suggests that the racemization proceeds by an oxidation-reduction sequence rather than involvement of a "racemase" enzyme. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.