91735-68-1

Upstream product

• 117856-45-8 1-benzyl-3-(3'-hydroxypropyl)-5-methoxy-3,6-dihydropyrazin-2(1H)-one 
• 88521-58-8 1-benzyl-3-(3-hydroxypropyl)-2,5-piperazinedione 
• 78999-54-9 1-benzyl-3-(3-t-butoxypropyl)-2,5-piperazinedione 
• 91735-67-0 1-benzyl-3-(3-t-butoxypropylidene)-6-hydroxy-2,5-piperazinedione 
• 59595-20-9 4-benzylpiperazin-2,5-dione 
• 117856-44-7 1-benzyl-3-<3'-(diphenyl-t-butylsilyloxy)propyl>-5-methoxy-3,6-dihydropyrazin-2(1H)-one 
• 104124-14-3 1-benzyl-5-methoxy-3,6-dihydropyrazin-2(1H)-one 
• 91735-62-5 1-benzyl-3-(3-t-butoxypropylidene)-2,5-piperazinedione 
• 88521-40-8 1-benzyl-3-(3-hydroxypropylidene)-2,5-piperazinedione 
• 91735-65-8 1-benzyl-3-(3-t-butoxypropyl)-6-hydroxy-2,5-piperazinedione 

Relevant academic research and scientific papers

Synthetic Studies on Bicyclomycin and its Analogues. Part 1. Synthesis of Substituted 2-Oxa-8,10-diazabicyclodecanes

Methods have been developed for formation of the eight-membered oxygen-containing ring system (2) present in the antibiotic bicyclomycin.The procedure starts with N,N'-disubstituted piperazine-2,5-diones or the corresponding mono imino ethers.A new method is based on the oxidation of the mono imino ethers using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as oxidant: the bis imino ethers gave pyrazines under these conditions, whilst the parent piperazinedione proved to be unreactive.