91735-77-2

Basic information

• Product Name: 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one
• Synonyms: 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one
• CAS NO: 91735-77-2
• Molecular Weight: 273.642
• Mol File: 91735-77-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one(91735-77-2)
• EPA Substance Registry System: 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one(91735-77-2)

Safety Data

• Hazardous Substances Data: 91735-77-2(Hazardous Substances Data)

Usage

General Description

1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one is a chemical compound with the molecular formula C14H8ClF3NO. It is a pyrrole derivative containing a 4-chlorophenyl group and a trifluoroethanone moiety. 1-(5-(4-chlorophenyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethan-1-one has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. It may exhibit various biological activities due to its structural features, such as its ability to interact with biological targets or enzymes. Further research and studies are needed to fully understand the properties and potential uses of this chemical in different fields.

Upstream product

• 19867-89-1 2-(4-chlorophenyl)-1H-pyrrole 
• 407-25-0 trifluoroacetic anhydride 
• 99-91-2 para-chloroacetophenone 
• 1956-39-4 4-chloroacetophenone oxime 

Downstream Products

• 1447004-25-2 1-[5-(4-chlorophenyl)-1H-pyrrol-2-yl]-2,2,2-trifluoro-1-ethanol 
• 1447031-58-4 2-(4-chlorophenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole 
• 1447031-65-3 2-(4-chlorophenyl)-5-{2,2,2-trifluoro-1-[5-(4-chlorophenyl)-1H-pyrrol-2-yl]ethyl}-1H-pyrrole 
• 1447031-70-0 4,4-difluoro-3-(4-chlorophenyl)-5-phenyl-8-trifluoromethyl-4-bora-3a,4a-diaza-s-indacene 
• 1447031-77-7 4,4-difluoro-3,5-bis(4-chlorophenyl)-8-trifluoromethyl-4-bora-3a,4adiaza-s-indacene 
• 131172-61-7 5-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid 

Relevant articles and documents

Synthesis of 5-Arylpyrrole-2-carboxylic Acids as Key Intermediates for NBD Series HIV-1 Entry Inhibitors

5-Arylpyrrole-2-carboxylic acids are important key intermediates in the synthesis of HIV-1 entry inhibitors (such as NBD-11021 and NBD-14010). Here we present a general method for the synthesis of some 5-arylpyrrole-2-carboxylic acids in three steps starting from pyrrole. By this method, the compounds could be prepared on gram scale and without chromatographic purification.

Synthesis and optical properties of difluorobora-s-diazaindacene dyes with trifluoromethyl meso-substituents

A series of meso-CF3-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dyes with aryl and hetaryl substituents at the C-3 and C-5 positions, both symmetric and asymmetric, have been synthesized in 36-90 % yields by a new strategy involving as the key step the condensation of 2,2,2-trifluoro-1-(5- arylpyrrol-2-yl)-1-ethanols with diverse 2-arylpyrroles. The starting 2,2,2-trifluoro-1-(5-arylpyrrol-2-yl)-1-ethanols are easily prepared by reduction of the available 2-trifluoroacetyl-5-arylpyrroles. The synthesized dyes fluoresce in a longer wavelength region (626-698 nm) with high quantum yield (0.84-0.99). A new strategy for the synthesis of highly efficient symmetric and asymmetric BODIPY fluorophores that combine trifluoromethyl and 3,5-aryl substituents has been developed. The key step is the P 2O5-promoted condensation of 2,2,2-trifluoro-1-(5- arylpyrrol-2-yl)-1-ethanols with diverse 2-arylpyrroles. Copyright