917377-31-2

Upstream product

• 917377-30-1 (+)-(3S,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-ol 
• 65-85-0 benzoic acid 
• 917377-28-7 benzoic acid (-)-(3S,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-hydroxytetrahydrothien-3-yl ester 
• 174833-54-6 (3S,4S,5R)-4-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-ol 
• 917377-29-8 benzoic acid (-)-(3S,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl ester 
• 917377-27-6 benzoic acid (+)-(3S,4S,5R)-4-benzyloxy-5-(tert-butyldiphenylsilanyloxymethyl)tetrahydrothien-3-yl ester 

Downstream Products

• 917377-32-3 (+)-(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-ol 
• 917377-33-4 (+)-3-benzoyl-1-[(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl]-1H-pyrimidine-2,4-dione 
• 917377-34-5 (-)-3-benzoyl-1-[(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 917377-35-6 (-)-1-[(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl]-1H-pyrimidine-2,4-dione 
• 917377-36-7 (-)-1-[(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 917377-38-9 (-)-9-[(3R,4S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-4-fluorotetrahydrothien-3-yl]-6-chloro-9H-purine 

Relevant academic research and scientific papers

Design, enantiopure synthesis, and biological evaluation of novel ISO-D-2′,3′-dideoxy-3′-fluorothianucleoside derivatives as a bioisostere of lamivudine

Novel iso D-2′,3′-dideoxythianucleoside derivatives 1-3 were designed and asymmetrically synthesized to search for new anti-HIV agents. Final compounds 1-3 were evaluated against a variety of viruses including HIV-1 and 2. Only cytosine analog 3 showed a

Design, synthesis, and biological evaluation of novel iso-d-2′,3′-dideoxy-3′-fluorothianucleoside derivatives

Novel iso-d-2′,3′-dideoxythianucleoside derivatives 1-4 were designed and asymmetrically synthesized as a bioisostere of lamivudine to search for new anti-HIV agents. The information about using sulfur participation occurred on DAST fluorination and Mitsu