917610-24-3

Upstream product

• 101376-26-5 (3R)-4-benzyl-3-(hydroxymethyl)-morpholine 
• 917610-10-7 tert-butyl {2-[(3R)-4-benzylmorpholin-3-yl]ethyl}carbamate 
• 917610-09-4 {2-[(3R)-4-benzylmorpholin-3-yl]ethyl}amine 
• 917572-28-2 (S)-4-benzyl-3-(chloromethyl)morpholine 
• 917610-12-9 tert-butyl (2-{(3R)-4-[1-(diphenylmethyl)azetidin-3-yl]morpholin-3-yl}ethyl)carbamate 

Downstream Products

• 917610-25-4 (2-{(3R)-4-[1-(diphenylmethyl)azetidin-3-yl]morpholin-3-yl}ethyl)dimethylamine 

Relevant academic research and scientific papers

NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES

The present invention relates to new azetidine derivatives of formula I, to pharmaceutical compositions containing said compounds and to the use of said compounds as neurokinin (NK) receptor antagonists in the treatment of gastrointestinal diseases. The invention further relates to processes for the preparation of compounds of formula I and to new intermediates used in the preparation thereof .