91787-26-7

Upstream product

• 17872-92-3 (phenylsulfonylmethyl)trimethylsilane 
• 120-92-3 cyclopentanone 
• 16003-66-0 ((dibromomethyl)sulfonyl)benzene 
• 19169-90-5 bromomethylphenylsulfone 
• 7205-98-3 chloromethyl phenyl sulfone 
• 158917-14-7 1-cyclopentanol 
• 65492-21-9 ((Iodomethyl)sulfonyl)benzene 
• 474126-65-3 acetic acid 1-(benzenesulfonyl-iodo-methyl)-cyclopentyl ester 
• 449172-24-1 acetic acid 1-(benzenesulfonyl-bromo-methyl)-cyclopentyl ester 
• 474126-64-2 acetic acid 1-(benzenesulfonyl-chloro-methyl)-cyclopentyl ester 
• 449172-22-9 1-(benzenesulfonyl-bromo-methyl)-cyclopentanol 

Relevant academic research and scientific papers

Samarium(II) iodide-mediated deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones: Synthesis of α,β-unsaturated sulfones

Deoxygenative debromination of α-bromo-β-hydroxy (acetoxy) phenyl sulfones with samarium(II) iodide led to substituted α,β-unsaturated sulfones in good to excellent yields. The E-isomer is the major product. A possible mechanism via an α-sulfonyl radical pathway is proposed.

A new method for synthesis of alkylidene sulfones via direct alkylidenating reaction of ketones with Gem-dibromomethyl sulfones promoted by the Sm/SmI2 system in the presence of a catalytic amount of CrCl3

Alkylidene sulfones were prepared in moderate to good yields via direct alkylidenating reaction of ketones with geminal dibromomethyl sulfones promoted by Sm/SmI2 system in the presence of a catalytic amount of CrCl3 under mild conditions.

Sm/Sml2/TiCl4(cat.) system promoted direct alkylidenating reaction of ketones with gem-dibromomethyl sulfones: A new method for preparation of alkylidene sulfones

Alkylidene sulfones were prepared in moderate to good yields via direct alkylidenating reaction of ketones with geminal dibromomethyl sulfones promoted by the Sm/Sml2 system in the presence of a catalytic amount of TiCl4 under mild conditions.

Synthesis of Alkenes via Peterson Reaction

The α-phenylthiosilanes (2) have been used to prepare the α-silyl anions (1) by reaction with lithium naphthalenide; subsequent condensation with a carbonyl compound gave the alkene (8) via the Peterson reaction.The α-phenylthiosilanes (2) were prepared from n,n-bis(phenylthio)acetals (4) by reaction with lithium naphthalenide and chlorotrimethylsilane.The n,n-bis(phenylthio)acetals (4) were obtained, in turn, from 1,1-bis(phenylthio)acetals (5) by anion formation with butyl-lithium-N,N,N',N'-tetramethylethylenediamine complex in hexane followed by reaction with an alkyl halide.The Peterson reaction was also used to prepare vinyl sulphides (9) and vinyl sulphones (13).

Reactions of α-Silylsulphones

α-Silylsulphones have been utilised to prepare vinylsulphones via the Peterson reaction and ketones by alkylation, reduction, and sila-Pummerer rearrangement.