917969-39-2

Upstream product

• 205582-88-3 methyl 2-methyl-6-(trifluoromethyl)nicotinate 
• 126747-14-6 4-cyanophenylboronic acid 
• 917969-37-0 4-(3-bromo-2-hydrazinylpyridin-4-yl)benzonitrile 
• 917969-36-9 4-(3-bromo-2-chloropyridin-4-yl)benzonitrile 
• 884494-53-5 3-bromo-2-chloro-4-iodopyridine 
• 681260-50-4 (2-methyl-6-(trifluoromethyl)pyridin-3-yl)methanol 
• 52200-48-3 3-bromo-2-chloropyridine 
• 917396-29-3 3-(chloromethyl)-2-methyl-6-(trifluoromethyl)pyridine 

Relevant academic research and scientific papers

Triazolopyridine cannabinoid receptor 1 antagonists

The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents, and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formula: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein R1, R2, R3, R4 and R5 are described herein.