91803-46-2Relevant academic research and scientific papers
Open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-Aryl hydrazones
La Regina, Giuseppe,Gatti, Valerio,Piscitelli, Francesco,Silvestri, Romano
experimental part, p. 2 - 6 (2011/04/15)
We reported the first example of open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-aryl hydrazones. Compounds were prepared in excellent isolated yields (88-98%) in only 5 min, by reacting 4- and 2,4-(di)substituted phenylhydrazines, bearing both electron-donating (4-CH 3, 4-OCH3) and -withdrawing (4-Cl, 4-Br, 4-CF3, 4-NO2, 2,4-Cl2) groups with 2-, 3-, and 4-acetylpyridine. The method was successfully extended to other carbonyl compounds.
