918142-80-0 Usage
Indole derivative
Contains a nitrile group and a chloro substituent, as well as a phenylsulfonyl functional group
Potential applications
Organic synthesis, pharmaceuticals and agrochemicals development
Biological activities
Potential as anticancer, antibiotic, and antiviral agents
Reactivity and interactions
Chloro and phenylsulfonyl groups could affect the compound's reactivity and interactions with biological targets, making it a subject of interest for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 918142-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,1,4 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 918142-80:
(8*9)+(7*1)+(6*8)+(5*1)+(4*4)+(3*2)+(2*8)+(1*0)=170
170 % 10 = 0
So 918142-80-0 is a valid CAS Registry Number.
918142-80-0Relevant academic research and scientific papers
NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
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Page/Page column 55, (2010/11/25)
Compounds of Formula I: Formula (I); are HIV reverse transcriptase inhibitors, wherein R1, R2, R3, R4 and R5 are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salt
Inhibitors of HIV reverse transcriptase
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, (2008/06/13)
Novel indole compounds inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
