918149-72-1 Usage
Description
(R)-3-(4-METHOXYPHENYL)PENT-4-ENOIC ACID, also known as 4-hydroxy-3-(4-methoxyphenyl)pent-4-enoic acid, is a chiral carboxylic acid derivative with a molecular formula of C12H14O4. It features a pentenoic acid group and a methoxyphenyl substituent, which contribute to its unique structural characteristics. (R)-3-(4-METHOXYPHENYL)PENT-4-ENOIC ACID has potential applications in organic synthesis and pharmaceutical research due to its distinct properties and possible biological activities.
Uses
Used in Pharmaceutical Research:
(R)-3-(4-METHOXYPHENYL)PENT-4-ENOIC ACID is used as a key intermediate in the synthesis of various pharmaceutical compounds for its unique structural features and potential biological activities.
Used in Organic Synthesis:
(R)-3-(4-METHOXYPHENYL)PENT-4-ENOIC ACID is used as a building block in the creation of complex organic molecules, taking advantage of its reactive functional groups and chiral nature.
Different applications in different industries may include its use in the development of new drugs, as a chiral catalyst in asymmetric synthesis, or as a component in the production of specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 918149-72-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,1,4 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 918149-72:
(8*9)+(7*1)+(6*8)+(5*1)+(4*4)+(3*9)+(2*7)+(1*2)=191
191 % 10 = 1
So 918149-72-1 is a valid CAS Registry Number.
918149-72-1Relevant articles and documents
Synthesis, characterization and antiproliferative activity of β-aryl-ω-iodo-γ-lactones
Wzorek, Alicja,Gawdzik, Barbara,Gladkowski, Witold,Urbaniak, Mariusz,Barańska, Anita,Malińska, Maura,Wo?niak, Krzysztof,Kempinska, Katarzyna,Wietrzyk, Joanna
, p. 160 - 168 (2013/10/22)
A convenient pathway for the synthesis of new of β-aryl-ω-iodo- γ-lactones is described. The synthetic route led to both cis and trans isomers which were separated by column chromatography or crystallization. The structures of synthesized compounds were confirmed by spectroscopic methods: IR, NMR and HR-MS. For lactones with naphthyl ring (6e and 7e) the crystal structures were also obtained. The lactones were screened for biological evaluation against cancer line HL-60 (human promyelocytic leukemia). The tests showed that the presence of substituent at the benzene ring does not significantly affect the antiproliferative activity of the compound.
An unusual β-vinyl effect leading to high efficiency and enantioselectivity of the amidase, nitrile biotransformations for the preparation of enantiopure 3-arylpent-4-enoic acids and amides and their applications in synthesis
Gao, Ming,Wang, De-Xian,Zheng, Qi-Yu,Wang, Mei-Xiang
, p. 9532 - 9535 (2007/10/03)
(Chemical Equation Presented) Biotransformations of 3-arylpent-4- enenitriles catalyzed by Rhodococcus erythropolis AJ270, a nitrile hydratase/amidase-containing microbial whole-cell catalyst were studied, and an unusual β-vinyl effect of the substrate on
