918307-19-4Relevant academic research and scientific papers
Synthesis of amino acid derived seven-membered lactams by RCM and their evaluation against HIV protease
Zaman, Shazia,Campaner, Pietro,Abell, Andrew D.
, p. 8323 - 8331 (2006)
A versatile synthesis of hydroxylated and epoxy 1-azepin 2-ones substituted at N1, C-3 and C-4 or C-7 has been developed. The sequence involves ring-closing metathesis of an amino acid derived diene amide, followed by either epoxidation or dihydroxylation
