918328-16-2Relevant academic research and scientific papers
Discovery of Highly Potent Liver X Receptor β Agonists
Kick, Ellen K.,Busch, Brett B.,Martin, Richard,Stevens, William C.,Bollu, Venkataiah,Xie, Yinong,Boren, Brant C.,Nyman, Michael C.,Nanao, Max H.,Nguyen, Lam,Plonowski, Artur,Schulman, Ira G.,Yan, Grace,Zhang, Huiping,Hou, Xiaoping,Valente, Meriah N.,Narayanan, Rangaraj,Behnia, Kamelia,Rodrigues, A. David,Brock, Barry,Smalley, James,Cantor, Glenn H.,Lupisella, John,Sleph, Paul,Grimm, Denise,Ostrowski, Jacek,Wexler, Ruth R.,Kirchgessner, Todd,Mohan, Raju
, p. 1207 - 1212 (2016/12/18)
Introducing a uniquely substituted phenyl sulfone into a series of biphenyl imidazole liver X receptor (LXR) agonists afforded a dramatic potency improvement for induction of ATP binding cassette transporters, ABCA1 and ABCG1, in human whole blood. The ag
LIVER X RECEPTOR (LXR) MODULATORS
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, (2015/03/28)
Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
