918334-11-9

Upstream product

• 918334-10-8 2,3-di-O-benzyl-4,6-O-di-tert-butylsilylene-α-D-galactopyranose 
• 545-06-2 trichloroacetonitrile 
• 48149-72-0 (2S,3R,4S,5R,6R)-2-Allyloxy-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 
• 918334-09-5 allyl 2,3-di-O-benzyl-4,6-O-di-tert-butylsilylene-α-D-galactopyranoside 
• 918334-08-4 allyl 4,6-O-di-tert-butylsilylene-α-D-galactopyranoside 
• 100-39-0 benzyl bromide 
• 85272-31-7 di-tert-butylsilyl bis(trifluoromethanesulfonate) 

Downstream Products

• 918334-17-5 (2S,3S,4R)-2-amino-3,4-bis(benzyloxy)-1-(2,3-di-O-benzyl-4,6-O-di-tert-butylsilylene-α-D-galactopyranosyloxy)nonane 

Relevant academic research and scientific papers

Novel synthesis of α-galactosyl-ceramides and confirmation of their powerful NKT cell agonist activity

α-Galactosyl-ceramide (1) has been identified as a powerful modulator of immunological processes through its capacity to bind CD1d molecules and specifically activate invariant natural killer (NK)-like T cells (iNKT cells). This paper describes the synthe